论文代写-CD24细胞蛋白在乳腺癌研究中的意义

通过本篇论文代写-CD24细胞蛋白在乳腺癌研究中的意义了解到,CD24是一种小细胞表面蛋白分子,在多种癌症[9]中与糖基磷脂酰肌醇结合。人们发现它们具有信号转换器的功能。它也被称为热稳定抗原簇。CD24 (HSA)[43]实际上是一种由CD24基因编码的蛋白质。这是在6号染色体上发现的。糖基化细胞表面蛋白CD24在乳腺癌研究中具有重要意义。CD24+癌细胞更容易在血流中扩散,并在次生器官中形成新的菌落[9,10]。CD24糖蛋白存在于淋巴细胞和某些神经母细胞中。编码的蛋白通过糖基磷脂酰肌醇(GPI)与细胞表面结合。人们发现CD24常与各种癌症的预后有关,接下来有关论文代写-CD24细胞蛋白在乳腺癌研究中的意义分析如下:

CD24 is a small cell surface protein molecule that has binded to the glycosylphosphatidylinositol in many kinds of cancer [9]. It is has been found that they function as a signal transducer. It is otherwise known as the cluster of differencation 24 or heat stable antigen. CD24 (HSA) [43] is actually a protein that is encoded by the CD24 gene. This is found on the chromosome 6. Heavily glycosylated cell surface protein CD24 is important in the study of breast cancer. CD24+ cancer cells tend to spread more easily in bloodstream and seed new colonies in secondary organs [9, 10]. CD24 glycoprotein is found in the lymphocytes and some kinds of neuroblasts. The protein encoded is found to be adjoined via glycosyl phosphatidylinositol (GPI) to the cell surface. It has been found that the CD24 is often associated with the prognosis of various cancers. The exact heuristics and the mechanism adopted by the CD24 are not clear. CD24 expression was analyzed in 747 breast cancer tissues. It was found that the CD24 was used in the DNA methylation and histone modification status in the promoter region of CD24. It was found that the patients who had higher levels of CD24 had shorter survival rates that with patients who had low CD24 [26]. It was also found from analysis that the gene expression of CD24 was involved in histone acetylation. This is an independent processing the DNA methylation [44]. This points to the mechanism of action of the epigenetic regulation of CD24. The result indicated that over gene expression of the CD24 gene causes lower survival rates [46].

Thus analysis of CD24 can be a potentially strong therapeutic target for the specific subtypes of breast cancer. CD24 is thus found to be more adept in diagnosing carcinoma owing to their enhanced functionality. It has been found that the glycosylation has diversity in the proteome. Every aspect of the glycosylation process can be changed or modified [38]. This includes the glycoside bond, glycerin composition, glycerin structure and also in the oligosachharide layer. From this analysis, it is found that glycosylation plays an important biochemical process and is involved in a number of biochemical pathways in the body. E-selectin is found to play an important role in this process. The reason for exploring the function of glycosylation and the CD24, CD44 gene expression is to understand the role of the glycosylation for the metastasis. Empirical research has found that glycosylation plays an important role in the metastasis function. Details are discussed in detail in the following.

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